Plasmodium falciparum-Infected Erythrocyte Knob Density Is Linked to the PfEMP1 Variant Expressed
ABSTRACT Members of the clonally variant Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family mediate adhesion of infected erythrocytes (IEs) to vascular receptors.PfEMP1 expression is normally confined to nanoscale knob protrusions on the IE surface membrane.To investigate the relationship between the densities of these IE surface